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Patients require lifelong hydroxocobalamin injections, typically 1mg every three months following an initial loading regimen (or every two months if there was neurological involvement)
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The elderly (reduced absorption) Pernicious anemia Vegetarians / Vegans (low dietary B12) People taking metformin or acid reflux medications (PPIs) Post-bariatric or gastric-bypass patients Genetic variants in MTRR , MTR , or TCN2 What Has B12 Been Studied For
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