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& DCCT/EDIC Research Group
the mitochondrial multienzyme complexes of 2-oxo acids, i.e., of pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH), 2-oxoadipate dehydrogenase (OADH) and branched chain 2-oxo acid dehydrogenase (BCODH), linked to amino acids through their transamination to the 2-oxo acids
Our sample was largely white and female, further studies in more diverse populations are needed to examine sex and race differences
Even though human studies have not shown the same effect, these drugs should not be used by people with a personal or family history of multiple endocrine neoplasia syndrome type 2 (MEN 2), a rare cancer that increases the risk for thyroid tumors
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