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The methods were prepared using the Cochrane Handbook and Review Manager (RevMan) version 5.4 software (The Nordic Cochrane Centre, The Cochrane Collaboration, 2020, Copenhagen, Denmark) and this paper was reported using the preferred reporting items for systematic reviews and meta-analysis (PRISMA) statement [4448]
Nrf2 overexpression inhibited the Tat effects, reducing the intracellular ROS and increasing intracellular levels of GSH [28]
Fat (adipose) tissue can release cytokines (cell-signaling molecules) such as tumor necrosis factor-alpha (TNF-) that interfere with the action of insulin (in this context, these cytokines are referred to as adipokines )
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