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Where Cannabis Enters the Conversation Cannabis interacts with the endocannabinoid system (ECS), a regulatory system that influences: Appetite Metabolism Mood Sleep Inflammation The ECS includes cannabinoid receptors throughout the central nervous system, immune system, and peripheral tissues

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[13] The FDA also considered data from one separate trial (NCT01720446 [76] ), which was sponsored by Novo Nordisk, of 3297 participants with type 2 diabetes who were at high risk for cardiovascular events