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Its small size gives it superior membrane permeability and potential oral bioavailability compared to conventional peptides

The D-amino acid substitution preserves the spatial orientation of amino acid side chains needed for competitive binding to the FOXO4-p53 interaction surface, maintaining biological activity despite the non-natural backbone (PMID: 28340339)

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These findings are one reason BPC 157 is often discussed as a possible recovery aid for tendon injuries