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Some GLP-1 RAs have further been shown to reduce cardiovascular events in patients with T2D who have eASCVD or severe target organ damage, independent of baseline HbA1c or concomitant glucose-lowering therapies [9, 14]
This is harder to detect because it requires noticing the absence of expected effects rather than the presence of visible problems
Results from the EVOKE trials, the largest clinical study to date with the GLP-1 drug semaglutide in Alzheimers disease, showed that semaglutide did not significantly slow disease progression in people with early-stage Alzheimers
Prioritize complex carbohydrates (vegetables, whole grains, legumes) over simple sugars
Studies indicate improvements in inflammatory markers, though again, distinguishing direct anti-inflammatory effects from those secondary to metabolic improvement remains challenging
