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Evolving transpeptidase and hydrolytic variants of -glutamyl transpeptidase from Bacillus licheniformis by targeted mutations of conserved residue Arg109 and their biotechnological relevance

Este efecto en cadena mejora an ms la defensa del organismo frente al dao oxidativo

Metabolomic results confirmed systemic glutathione depletion and mitochondrial dysfunction, as evidenced by reduced levels of S-lactoylglutathione, carnitine species, and NAD+ intermediates

10.1186/cc11930 133 TsoiJ.RobertL.ParaisoK.GalvanC.SheuK

This is where Phase II detoxification, specifically a process known as glutathione conjugation, becomes critical