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Results GSH prevented long-term oscillating glucose (LOsG) intake-induced prediabetes in rats To mimic human food-intake habits in rodents, we orally (by gavage) gave female rats who were having regular rat chaw an extra 6 g/kg of d-glucose every 6 h per day for 38 days (P38), which resulted in an extra 1.6 times of sugar than what they usually have
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Structurally, AOD 9604 retains a disulfide-linked cyclic conformation formed by cysteine residues, preserving key features of the native GH region responsible for lipid metabolism signaling
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