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( i ) Fasting plasma GIP (n = 5 per group), ( j ) total GLP-1 (CON n = 9, Gipr AP-KO n = 8), ( k ) insulin (CON n = 5, GIPR AP-KO n = 4), (l) food intake post IPGTT (CON n = 6, Gipr AP-KO n = 6), ( m ) ad lib fed blood glucose (CON n = 6, Gipr AP-KO n = 6), (n) RER (time x group F(24, 168) = 1.739 p = 0.023), ( o ) energy expenditure (with ANCOVA using BW as covariate), ( p ) ambulatory activity (x beam breaks)

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Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice

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