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A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism

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In the tumor microenvironment, this metabolic adaptation likely enables tumor cells to continue growing under adverse conditions, suggesting that glutamine metabolism may serve as a critical compensatory mechanism in iron-deficient states

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In a 10-year follow-up study of 751,792 type 2 diabetes mellitus (T2DM) patients in Taiwan, the incidence of epilepsy was higher in T2DM patients than in controls (35.0 and 21.9 per 10,000 person-years, respectively), and T2DM increased the risk of epilepsy by approximately 50% (81)

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