However, contact your healthcare provider immediately if you experience: Call Right Away: Severe, persistent vomiting that prevents you from keeping down any fluids Signs of dehydration: dark urine, dizziness when standing, extreme fatigue, confusion Severe abdominal pain that doesn't improve or is getting worse Signs of pancreatitis: intense upper abdominal pain radiating to back, fever, nausea Allergic reaction: rash, swelling, difficulty breathing Low blood sugar symptoms (if you have diabetes): shaking, sweating, confusion, blood sugar below 70 mg/dL Vision changes (especially if you have diabetes) Call During Office Hours: Nausea so severe you can't eat anything for more than 24 hours Constipation lasting more than 4-5 days despite interventions Persistent heartburn not relieved by over-the-counter medication Questions about adjusting other medications (especially diabetes meds) Concerns about whether your symptoms are normal Normal First-Week Symptoms (Don't Need to Call): Reduced appetite Mild to moderate nausea, especially days 2-4 Feeling full very quickly Mild fatigue Some constipation Mild headaches Food aversions or different taste preferences Frequently Asked Questions What should I eat during my first week on Ozempic or Wegovy

Symptoms may include dull aching pain, throbbing, or pressure in the head
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Semaglutide isnt recommended during pregnancy due to limited safety data in pregnant women
This work was supported by the National Natural Science Foundation of China (grant numbers 82203581, 82102925, and 82303366), the China Postdoctoral Science Foundation (grant numbers 2021M691469 and 2022M721526), the Guangdong Basic and Applied Basic Research Foundation (grant numbers 2020A1515110872, 2021A1515111220, and 2022A1515110165), the Guangzhou Science and Technology Plan Project (202201011554 and 2023A04J2378), the Key-Area Research and Development Program of Guangdong Province (grant number 2022B0303020003) and the President Foundation of Nanfang Hospital, Southern Medical University (grant number 2020C007) and the College Students Innovative Entrepreneurial Training Plan Program (grant number 202312121319)