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10.1016/j.regpep.2012.12.007 9 BecejacT.CesarecV.DrmicD.HirslD.MadzaracG.DjakovicZ.et al (2018)

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Finally, BDNF expression was significantly upregulated in CR-fed 3xTg males, which aligns with the improvements in AD pathology, particularly the tau-specific improvements in the males (Fig

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It extends beyond a simple aging process, involving irreversible and progressive neurological degeneration that impairs brain function through multiple etiologies