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29 In terms of the nervous system, GLP-1 receptor (GLP-1R) expression is enriched in central nervous system (CNS) regions, including the hypothalamus, which regulates appetite, and the brainstem, which primarily secretes brain-derived GLP-1, as well as in the peripheral vagus nerve

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In fact, if you go back to the worm studies that I was talking about, that was one of the first things

You eat less because you feel satisfied sooner

Annual Review of Psychology, 53 (1), 371-399