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A 2025 structured review, analysing 13 studies across clinical trials and observational data, suggests that vitamin D supplementation of at least 2,000 IU per day for 12 weeks increased levels of a protein that supports the survival and growth of brain cells, called BDNF, by approximately 7%, while also reducing scores on validated measures of depressive symptoms[6 Trusted Source 2025 - Nutrients Impact of Vitamin D Status and Supplementation on Brain-Derived Neurotrophic Factor and Mood-Cognitive Outcomes: A Structured Narrative Review ]
Promotes a healthy gut
Jani M et al
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