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Int J Mol Sci 24:2019 Ejike UC, Chan CJ, Okechukwu PN, Lim RLH (2020) New advances and potentials of fungal Immunomodulatory proteins for therapeutic purposes
Others prefer continuous low-dose approaches
88 STAT3 forms complexes with TOX, directly binding promoters of inhibitory receptors such as PD-1, TIM-3, and LAG-3, increasing chromatin accessibility and enforcing an exhausted phenotype
Tumor cells, in their quest for survival and proliferation, generate abnormally high levels of oxidative stress, partly due to increased cellular redox buffer GSH (87)
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