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Shaking introduces air bubbles and creates cavitation forces (micro-scale pressure waves) that denature peptide chains

Loboda A, Damulewicz M, Pyza E et al (2016) Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

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doi: 10.1210/jcem.87.3.8165 10 RazviSBhanaSMrabetiS

Apply it after meals, before bed, and before going out in the sun