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Biswas, P., Dellanoce, C., Vezzoli, A., Mrakic-Sposta, S., Malnati, M., Beretta, A., & Accinni, R

LPS stimulation significantly induced the phosphorylation of NF-B p65 at Ser536 and promoted its nuclear translocation

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The intravenous route was chosen for administration of the parenteral control since this would ensure greatest reproducibility of entry into the bloodstream, and would match more closely the time course of entry of peptide from the intestine, which is seen to be rapid

Going higher does not always mean losing faster, but it almost always means more side effects