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Vitamin B12 injections can contain cobalt, which can also cause an allergic reaction
18 Prevention Because of potential interactions from prolonged medication use, physicians should consider screening patients for vitamin B 12 deficiency if they have been taking proton pump inhibitors or H 2 blockers for more than 12 months, or metformin for more than four months
Diversity, mechanisms, and significance of macrophage plasticity
Repeatedly injecting into the same spot can lead to lipohypertrophy a build-up of fatty, fibrous tissue beneath the skin which can impair drug absorption and reduce the predictability of the medication's effect
Another strategy is to take supplements with food or at night before going to bed to prevent stomach irritation
