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GLP-1 medications suppress appetite and slow digestion, but you can build muscle on GLP-1 by prioritizing resistance training and consuming adequate protein relative to your lean mass, not total bodyweight

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There is adequate preclinical evidence that retatrutide (LY3437943) attains that balance and improves glucose control and lipid metabolism

[5] [6] Clinical trial data from the SURPASS and SURMOUNT studies demonstrate that gastrointestinal adverse eventsincluding nausea, diarrhea, vomiting, constipation, and abdominal discomfortoccur frequently with tirzepatide

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