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In 2003, for example, a multi-year study published in Neuroendocrinology Letters found that epithalamin could normalize the basic functions of the human organism, potentially extending lifespan by improving cardiovascular, endocrine, immune, and nervous function, as well as homeostasis and metabolism.2 Several publications including two systematic reviews in Advances in Gerontology have corroborated such findings.3 4 Researchers believe that epitalons therapeutic qualities may be due to the following mechanisms of action: Telomere elongation Telomeres are caps of DNA sequences at the ends of chromosomes
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Similarly, in bipolar disorder, particularly during depressive episodes, patients exhibit altered energy metabolism marked by increased lactate levels and decreased glucose and glycine levels, which parallels results in ME/CFS that suggest TCA impairment and energy metabolism dysregulation (Yamano et al., 2016
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