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Hormonal status: Perimenopausal and postmenopausal women may see a slower response due to estrogen-driven collagen decline
Due to inclusion of patients only with early-stage ALS, noninvasive or invasive ventilatory support and patient mortality did not occur during the 16-week trial period, rendering secondary endpoints ineffective
Cardiovasc Res 2024: ivabradine, a funny-current (HCN/I_f) blocker, does not abolish the effect, which places the chronotropy on the SR calcium clock rather than the funny channel
Emergency services often qualify
