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Compounds such as thalidomide and its analogs lenalidomide and pomalidomide promote interactions between E3 ligases (e.g., cereblon) and specific target proteins, triggering their ubiquitination and proteasomal degradation
The pathological role of advanced glycation end products-downregulated heat shock protein 60 in islet -cell hypertrophy and dysfunction
It also helps to reduce the ageing process of the skin
Peptides can interact in solution, potentially degrading each other or forming inactive complexes
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