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The thing that I think is happening with GLP-1s again, and that specifics perhaps to the caloric part of alcohol is that they are taking away the motivation to drink
Research suggests that GLP-1s may affect immune cells and lower levels of inflammatory cytokines, such as TNF and IL-6, which are also involved in RA
As of 23 September 2025, the TGAs Database of Adverse Event Notifications (DAEN) contains the following: 72 reports for suicidal ideation 6 reports for depressional suicide 4 reports of suicide attempt 2 reports of completed suicide 1 report of self-injurious ideation
If you develop signs of high cortisol like central weight gain despite overall weight loss, morning headaches, or mood disturbances, testing cortisol through saliva or 24-hour urine collection may be appropriate
However, it may cause more discomfort or stinging compared to a room-temperature injection
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