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It is believed that when melatonin binds to these receptors, SCN neuronal activity is decreased, slowing brain function and creating the feeling of tiredness

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CrossRef Development of a Community-Based Palliative Care Model for Advance Cancer Patients in Public Health Centers in Busan, Korea Sook-Nam Kim, Soon-Ock Choi, Seong Hoon Shin, Ji-Sun Ryu, Jeong-Won Baik Cancer Research and Treatment.2017