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Indeed the activation of prodrugs in GST overexpressing cells may lead to high concentrations of an active drug, as compared to normal cells with moderate enzyme levels
Acta Paediatr (1994) 83(2):18891.10.1111/j.1651-2227.1994.tb13048.x 87 ButteNFGoldblumRMFehlLMLoftinKSmithEOGarzaCet alDaily ingestion of immunologic components in human milk during the first four months of life
Indeed, the data above show that all forms of vitamin B12 administered to patients with deficiency are catalyzed at this stage by glutathione, during which all axial Co-C or Co-O chemical bonds are broken, and the central cobalt atom of all forms receives an electron or a large part of the electron density reaching one electron during the reaction from the monoanion of glutathione
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RESEARCH BRIEFINGS A common genetic variant of the human leukocyte antigen (HLA) complex, a family of genes involved in the immune response, is associated with an absence of symptoms during SARS-CoV-2 infection
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