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A major challenge was that native GLP-1 is rapidly degradedwithin about two minutesby the enzyme dipeptidyl peptidase-4 (DPP-4)
The medications dose gradually increases, depending on your bodys response to treatment
How to do it: Aim for around 80120 grams of protein per day
Tirzepatide cannot be compounded into an oral formulation and therefore is available for subcutaneous injection only
When elevation persisted on a second measurement, the association with incident solid cancer was strong, while a transient elevation carried no greater risk than a normal value
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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