doi: 10.3389/fphar.2025.1526270 Received 11 November 2024 Accepted 28 January 2025 Published 17 February 2025 Volume 16 - 2025 Edited by Alessandra Linardi, Santa Casa de So Paulo School of Medical Sciences, Brazil Reviewed by David Pubill, University of Barcelona, Spain Ariadiny Lima Caetano, Santa Casa de So Paulo School of Medical, Brazil Updates Copyright 2025 Wang, Hao, Ma, Feng, Yang, An, Su and Feng
When optimized and properly administered, B12 plays a crucial role in everything from red blood cell production to nerve function to metabolism
In methyl vitamin B12 deficiency, there is reduced production of S-Adenosylmethionine (SAM), and the activity fo the enzyme cystathionine beta synthase is reduced, thus leading to reduced transfer of the sulphur from methionine into the sulphation cycle, with a resultant lack of production of Glutathione
& Lippard, S
Acute partial tears represent more severe injuries where tendon fibers have ruptured but the tendon maintains overall continuity