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In the single source study, AHK-Cu stimulated the proliferation of cultured human DPCs and the elongation of isolated human hair follicles at very low concentrations (1010 M), raised the Bcl-2/Bax ratio and lowered cleaved caspase-3 and PARP though the drop in apoptotic-cell count itself was not statistically significant [1]

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PMID: 21593563 [vi] Park SA, Byeon G, Jhoo JH, Kim HC, Lim MN, Jang JW, Bae JB, Han JW, Kim TH, Kwak KP, Kim BJ, Kim SG, Kim JL, Moon SW, Park JH, Ryu SH, Youn JC, Lee DW, Lee SB, Lee JJ, Lee DY, Kim KW

The rupture of the physical barrier (OMM) that limits their release into the cytosol constitutes a point-of-no-return in cell death (Martinou and Green, 2001

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