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Oxidative stress is an important pathological mechanism of UC [44]
Furthermore, activation of memory CD8 + T cells through CD8 antibody-mediated stimulation triggers downstream signaling of the T cell receptor, enhancing T cell-mediated cytotoxicity and promoting the production of effector cytokines, which is dependent on glucose and glutamine [133]
After 3 h, the medium was removed and replaced with medium as follows: HUVEC and HDMEC were cultured in endothelial cell basal medium supplemented with 2% (HUVEC) or 1% (HDMEC) FCS, and 90 g ml 1 heparin, with or without hHGF or dimeric macrocycle
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