[20] For specific conditions studied in clinical trials, higher dosessometimes 300 to 600 mg dailyhave been used under medical supervision, though evidence supporting such high doses varies by indication
300 , 161169 (2010) Leclercq, R., Derlot, E., Duval, J
Sublingual B12: Pros and Cons Sublingual B12 supplements dissolve under the tongue, where some of the vitamin may be absorbed through the tissues in the mouth before being swallowed
619623., doi:10.1016/j.semcdb.2011.05.005
445,446 Extensive research has shown that omega-3 PUFAs exert pleiotropic regulatory effects on virtually all immune cell populations, including but not limited to T cells, B lymphocytes, macrophages, and neutrophils, thereby increasing their functional competence