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Pharmacologically, GLP-1R is a G-protein coupled receptor (GPCR) critical for glucose homeostasis, which mediates the effects of GLP-1R agonists [26, 27]

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Reduced inflammation in preclinical models has informed hypotheses for future clinical applications under controlled conditions

Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes (SUSTAIN-6 retinopathy data)