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Retatrutide improves insulin sensitivity through GLP-1 and GIP pathways, while growth hormone can transiently increase insulin resistance
( H ) Intraperitoneal glucose tolerance test following intraperitoneal glucose in male ( n = 8/9) and female ( n = 9/6) F10 f/f Villin Cre and littermate F10 f/f control mice on a HFD for 14 weeks
This allows nutritional deficiencies to grow
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