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Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors

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What the research actually covers Characterised as the first selective compound of its class (Raun et al., 1998) Comparatively little effect on cortisol and prolactin No human trials measure whether it builds muscle or improves strength Mechanism is well described

A well-balanced diet combined or not with exercise induces fat mass loss without any decrease of bone mass despite bone micro-architecture alterations in obese rat