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Bregman is a board-certified foot and ankle surgeon with nearly 30 years in practice 15 of which have been in Las Vegas

For questions about specific products, substances, and methods, contact USADAs Drug Reference Line at [email protected] or call (719) 785-2000, option 2.

Dose Range: 2050 mcg daily with gradual titration

Common and Serious Side Effects Potential Side Effects Electrolyte imbalance (potentially fatal) Dehydration from fluid and mineral loss Rectal burns from excessively hot coffee Bowel perforation (rare but extremely serious) Bacterial infections including sepsis Colitis and inflammation of colon lining Cramping, bloating, and nausea Dependence on enemas for normal bowel function Safety Measures Strict temperature control (37-40C maximum) Sterile, medical-grade equipment only Proper client screening and health history Monitoring for adverse reactions during procedure Limiting frequency to prevent dependence Ensuring adequate hydration before and after Professional training in enema administration Emergency protocols for complications Absolute Contraindications Coffee enemas should never be administered to people with certain conditions

Two cold-set lines of tomato, Balkan and Jemnorrosnij, were crossed and selections were made from the segregating generations of plants that set fruit at up to 8 C