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In these studies, participants with obesity achieved up to a remarkable 24.2% mean body weight reduction at 48 weeks
The early results on semaglutide are encouraging too, with most patients seeing measurable changes within the first four to eight weeks, though the full effect takes longer to manifest
During the phase 2 trial of orforglipron, it was found to help people lose body weight up to 15% after 8 months of use
The shortages have made it difficult for some people to get GLP-1 agonists even those with health insurance coverage for the drugs
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