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Head-to-Head Superiority (SURMOUNT-5): The SURMOUNT-5 trial, with detailed results published in The New England Journal of Medicine on May 11, 2025, directly compared Tirzepatide (Zepbound) with semaglutide (Wegovy)

The stronger feeling of hunger subsides within a few months

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If you're using a high-concentration product and experiencing issues, switch to 2% to 4% and observe