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Deficiency is common, especially in people who follow a vegetarian or vegan diet
[15]J.J
Oncol Lett 2018;15:433440
In mice, the bulk of the metabolic improvement seen upon FGF21 treatment derives from centrally mediated weight loss, whereas FGF21 analogs elicit limited weight loss in humans
however, some individuals may experience mild skin sensitivity depending on: Formulation concentration Skin type Frequency of cosmetic application Concurrent cosmetic ingredients Possible Cosmetic Reactions Mild redness Temporary tingling sensations Skin irritation Dryness Increased skin sensitivity Temporary blue discoloration when higher concentrations are utilized Higher concentrations are not always preferred and may increase the likelihood of cosmetic skin irritation, particularly in sensitive-skin formulations
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