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The liver, stocked with glycogen (a glucose polymer), steps up immediately through glycogenolysis breaking it down into usable glucose

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Glucagon receptor: Increases hepatic glucose production (paradoxically beneficial at controlled levels), significantly boosts energy expenditure , and promotes fat breakdown (lipolysis)

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Schuster J, Mitchell ES

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Tirzepatide (Zepbound) reached 22.5% in SURMOUNT-1, and in SURMOUNT-5 showed 20.2% versus 13.7% for semaglutide over 72 weeks

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Obesity and recurrent spontaneous abortion: the crucial role of weight management in pregnancy

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