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Tail vein samples were obtained for immediate glucose measurement as above, or into lithium heparin-coated microvette tubes for plasma insulin measurement using a mouse insulin-specific HTRF (Cisbio)

Otros frmacos en desarrollo Otros multiagonistas basados en GLP-1 con otros pptidos, como GIP, GCG, PYY, secretina, GLP-2, as como nuevos triagonistas y tetraagonistas (aadiendo agonismo DACRA), se encuentran en fases iniciales de su desarrollo1,59 (tabla 2)

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Moreover, mice receiving GLP-1 monotherapy displayed significantly lower insulin levels compared with mice that were treated with MK-801 alone