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The complex interplay between diabetes and cancer risk presents additional challenges in understanding the role of GLP-1RAs
The lifestyle interventions should be monitored, adapted, and perpetuated in an informed consent with the patient over the years, regardless of whether additional medical or surgical therapy is started in the course of T2D or obesity ( Incretin-based therapies Incretins are hormones that are secreted from enteroendocrine cells in the gut mucosa after a meal
In a clinical context, lack of FDA approval for most gut peptides means no standardized dosing or documented human safety profiles
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