does tirzepatide or semaglutide have more side effects vs Effects: What's Worse? Tirzepatide vs. Semaglutide: Key Differences

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Because Wegovy (when approved at its highest dose) produces rapid weight loss and sharper metabolic shifts, this could drive the stronger association by predisposing to optic nerve hypoperfusion through intravascular volume contraction, hypotension with nocturnal dips and autonomic instability. For ophthalmologists, the findings highlight a potential safety signal that warrants further investigation but should be interpreted cautiously

During transport, use insulated cooling bags with ice packs when necessary, ensuring the medication does not come into direct contact with ice to prevent freezing

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Zeng Q, Xu J, Mu X, Shi Y, Fan H, Li S (2023) Safety issues of tirzepatide (pancreatitis and gallbladder or biliary disease) in type 2 diabetes and obesity: a systematic review and meta-analysis