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While GLP-1 RAs have provided an important new weapon for those suffering from profound obesity, they unfortunately trigger the same counter-productive mechanisms as other weight-loss efforts, which rely on caloric restriction, resulting in muscle loss, which limits the fat loss and metabolic benefit
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The combined hormonal activation leads to reduced calorie intake, increased satiety, and enhanced lipid oxidation , yielding potent weight loss and glycemic control [8] [9]
Read more: Semaglutide side effects: Symptom guide & management tips Frequently asked questions about going on a semaglutide maintenance dose Why do people gain weight after stopping semaglutide
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