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A common alternative is to extend the 0.5 mg phase to 8 weeks (two months at 0.5 mg instead of one) if gastrointestinal side effects are significant
Mechanism of Action Tirzepatide (brand names Zepbound and Mounjaro) and semaglutide (Ozempic, Rybelsus, and Wegovy) are glucagon-like peptide-1 (GLP-1) receptor agonists
Trans Assoc Am Physicians 1967
Zummo FP, Cullen KS, Honkanen-Scott M, Shaw JAM, Lovat PE, Arden C
Human Psychopharmacology: Clinical and Experimental, 23(8), 693-705
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