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A population-based cohort study using data from the Clinical Practice Research Datalink database (20072012) concluded that GLP-1RAs were not related to a decreased risk of bone fractures, independent of dose accumulation and the type of GLP-1 drug (exenatide or liraglutide) used (20)
These trials were not head-to-head the populations, durations and protocols differed so the comparison is indicative rather than definitive
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The cumulative risk is what matters
WilsonPWFMeigsJBSullivanLFoxCSNathanDMD'Agostino RBSr
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