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267,268 Under oxidative stress conditions, Nrf2 dissociates from Keap1 following thiol modifications of its cysteine residues, preventing Nrf2 ubiquitination and proteasomal degradation

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Visible improvements typically occur at 46 weeks

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doi: 10.3389/fendo.2023.1085041 Received 31 October 2022 Accepted 26 January 2023 Published 07 February 2023 Volume 14 - 2023 Edited by Tarunveer Singh Ahluwalia, Steno Diabetes Center Copenhagen (SDCC), Denmark Reviewed by Piotr Konopelski, Medical University of Warsaw, Poland

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