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While enteral administration offers several advantages over other routes of drug delivery in terms of convenience, promoting medication compliance, it faces several obstacles, of which the most widely recognized are inefficient absorption owing to physical barriers and an acidic microenvironment, along with degradation by proteases and the first-pass metabolism in the liver

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Its harder to study females because we have hormonal changes

3 Synthetic GLP-1 agonists are resistant to degradation by DPP-4, increasing the half-life of their actions by several fold

Its job is to move fatty acids into mitochondria, where they can be oxidised, or burned, for energy [1]