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Rev Endocrine Metab Disord (2022) 23(3):52139
Topical application is limited by the stratum corneum barrier, with near-zero penetration through intact skin (Li et al., 2015)
In fact, some of the most common symptoms of deficiency include hyperpigmentation of the skin and nails, hair changes, vitiligo, and angular stomatitis, which is a condition that causes cracks and inflammation in the corners of the mouth
Injection site reactions: Both compounds, if used in injectable form, carry risks of localised reactions including redness, swelling, pain, and infection
These small changes are the earliest visible signs of the transformation that will accelerate dramatically over the coming months
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