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Mazzoli and Pessione (2016) reported several strains that regulate the hypersensitivity of the intestinal viscera of IBS rats, such as Lactobacillus brevis and Bifidobacterium dentate , can also produce GABA (-aminobutyric acid)

Manufactured drugs are standardised, therefore their standard formulations can go through testing to determine how long the manufacturer can guarantee safety or potency