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DOHH is a dinuclear iron enzyme that is required for the posttranslational modification of a single lysine residue on eukaryotic initiation factor 5A (eIF5A, Park et al., 2010)
NaBPC157 was applied as a prophylactic co-treatment or therapeutic salutary regimen (10 g or 10 ng/kg i.p.)
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A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment
The results showed that the proportion of SA--gal positive cells after OGD treatment was significantly higher than that in the control group (Figure 3D)
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