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However, ICIs can evoke demyelinating disorders in the CNS ( etc ) ( 4 Conclusion We briefly summarized the recent progress regarding the beneficial effects GLP-1RAs on myelin formation and maintenance and their potential efficacy toward MS and other demyelinating disorders

10.1136/gut.39.3.416 238 RomeroM

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If you develop a persistent, unexplained change in bowel habit particularly if you are aged 40 or over or have other risk factors your GP may wish to assess you in line with NICE guidance on suspected cancer (NG12), which sets out referral thresholds for persistent bowel changes

Further, they are also beneficial for those living in high-stress environments and interacting with daily pollutants and toxins